In present investigation, a series of 3,5-di (substitued)phenyl- 2-pyrazolines (2a-h) and 1-phenyl-3,5-di (substitued) phenyl- 2-pyrazolines(2i-p) were prepared by cyclization of hydrazine hydrate and phenyl hydrazine with α, β-unsaturated ketone (chalcones, 1a-h) using DMF solvent .The newly synthesized 2-pyrazolines were characterized on the basis of elemental analysis and spectroscopic data. The newly synthesized title compounds have been tested for their antibacterial activity. Some of the compounds exhibited encouraging results.
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